Postdoc in ovarian cancer chemical systems medicine in the Wennerberg Group at BRIC

Københavns Universitet (KU)

Fuldtidsjob
Ph.d. & forskning
Storkøbenhavn
Øresundsregionen

We are looking for a highly motivated and dynamic researcher for a 3-year postdoc position to commence mid-2019. The postdoc will explore experimental approaches to discover new ways to target the mechanisms of phenotypic plasticity in the development of chemoresistance in ovarian cancer.

Information on the department can be found at: www.bric.ku.dk.

Our research
The Wennerberg group at BRIC focuses on identifying new effective precision cancer therapies. This is done with a systems-driven approach where we combine chemical biology, phenotypic profiling, molecular profiling and informatics to gain understanding of individual cancers, their drug sensitivity and resistance mechanisms and how these may be targeted. Our ultimate goal is that our results will lay the foundation for new types of cures for individual and subsequently larger groups of cancer patients.

Your job
We are seeking a postdoc to study the role of the mechanisms of phenotypic plasticity in ovarian cancer recurrence, and to identify clinically relevant agents to overcome or prevent chemoresistance in high-grade serous ovarian cancer. The successful candidate will integrate the clonal drug response data with functional genomics and molecular profiling with the goal of discovering new ways to target determinants of phenotypic plasticity underlying ovarian cancer chemoresistance. The postdoc is encouraged to design innovative methodologies to address the clinically relevant questions in the field, depending on her/his expertise and interests.

Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

Essential experience and skills:

  • A PhD in Life Sciences or equivalent.
  • An excellent research track record.
  • Ovarian cancer biology and cancer drug response research.
  • Gene editing and functional genomics.
  • High throughput screening and high throughput imaging assay design.
  • Solid tumour ex vivo cell cultures.
  • A team player with leadership skills.
  • Proficient communication skills.
  • Excellent English skills written and spoken.

Desirable experience and skills:

  • Multi-omics research.

Place of employment
The employment is at BRIC, University of Copenhagen. BRIC is located in the Copenhagen Biocenter, close to the centre of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories and a number of core facilities shared between the 23 research groups at BRIC and the neighboring Finsen Laboratory. We have weekly journal clubs, data clubs, seminars with invited speakers and a young researchers club ASAP and our own PhD programme, MoMeD and our own Postdoc Career Programme. BRIC actively participates in the European alliance, EU-life consisting of 13 excellent life science research institutions http://eu-life.eu/.

Terms of employment
The employment as postdoc is a full time and fixed-term position for 3 years. Starting date is June 2019 or after agreement.

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts at 33,700 DKK/approx. 4,500 Euro (October 2018-level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.

Questions
For further information please contact Krister Wennerberg by e-mail; krister.wennerberg@bric.ku.dk.

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

    • Motivated letter of application (max. one page).
    • CV incl. education, work/research experience, language skills and other skills relevant for the position.
    • A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
    • List of publications.

    Application deadline: 18 February 2019, 23.59 p.m. CET.

    We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

    The further process
    After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

    You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

    The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

    University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.

    Københavns Universitet giver sine knap 10.000 medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.

    Info
    Ansøgningsfrist: 18-02-2019

    Ansættelsesdato: 01-06-2019

    Arbejdstid: Fuldtid

    Afdeling/Sted: Biotech Research & Innovation Centre (BRIC)


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    Fuldtidsjob
    Ph.d. & forskning
    Storkøbenhavn
    Øresundsregionen
    Kemi, Biotek & Materialer
    Naturvidenskab
    Forskning & Udvikling
    Naturvidenskab
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