Multifunctional biologics for enhanced tumor imaging, cell tracking and treatment

Aarhus Universitet (AU)

Ph.d. & forskning
Østjylland (Aarhus)

Applications are invited for a PhD fellowship/scholarship at Graduate School of Science and Technology, Aarhus University, Denmark, within the Nanoscience programme. The position is available from 1 May 2020 or later.

Title:
Multifunctional biologics for enhanced tumor imaging, cell tracking and treatment

Research area and project description:
The project aims to create new multifunctional nanostructures that can target and treat tumors by targeting multiple disease-specific receptors. The project will explore new bioconjugation chemistry to improve targeting and pharmacokinetic profiles in pre-clinical model systems. It will also focus on incorporating new innovative barcoding systems that can label cells in vitro and in vivo for subsequent multiomics analysis. Implications of the gained knowledge are early disease monitoring and more effective medicine with minimum of side-effects. The project is conducted in close synergy between multidisciplinary groups at iNANO and international clinicians.

This PhD project is part of the Center for Multifunctional Biomolecular Drug Design - CEMBID - funded by the Novo Nordisk Foundation. Based on interdisciplinary work in chemistry, molecular biology, pharmacology, and medicine, CEMBID aims to develop new multifunctional biomolecular drugs, which will pave the way for new types of drugs that are more effective, have fewer side effects, and can be adapted to the individual patient. Find more information about the center at www.cembid.au.dk.

Qualifications and specific competences:
Applicants to the PhD position must have a relevant Master’s degree in molecular biology or nanoscience or equivalent. Competences in nucleic acid/protein biochemistry will be an advantage. It is very important that the applicant is a good team player and scientifically broad-minded.

Place of employment and place of work:
The place of employment is Aarhus University and the work place will be at Interdisciplinary Nanoscience Center, iNANO (www.inano.au.dk).

iNANO was established in 2002 and at present is a major research and education center based at Aarhus University hosting 60 senior scientists, ~100 PostDocs and ~100 PhD students. The center combines expertise and faculty from Physics, Chemistry, Molecular biology and Medicine to carry out world class interdisciplinary research in Nanoscience and Nanotechnology. The center gives access to a broad range of infrastructure, tools and expertise including clean-room facilities. With a 5 year undergraduate nanotechnology programme and nanoscience graduate programme (www.inanoschool.au.dk) the center provides a full educational environment. In addition to the large base of basic research, the center has a large number of ongoing industrial projects and partnerships.

Contacts:
Applicants seeking further information are invited to contact:
Jørgen Kjems, jk@mbg.au.dk

Application procedures

Before you applyInformation and attachments:
Please be aware that you must have all relevant appendices, attachments, addresses for referees, etc. ready when you apply, as the entire application must be uploaded to the system in one go.

Documentation of language skills:
The English language requirement at GSST is comparable to an “English B level” in the Danish upper secondary school (“gymnasium”).

English language qualifications comparable to an “English B level” are documented by one of the following tests:

  • TOEFL test, minimum score: 560 (paper-based test) or 83 (internet-based test). The paper-based test must have a “total score”. From the August 2019 call, GSST will no longer accept the paper-based test.
    Aarhus University does not accept the TOEFL ITP test. Aarhus University’s TOEFL code is 8935. Ask the test centre to send your test results to Aarhus University, in order to enable verification of your test results.
  • IELTS (academic) test, minimum average score: 6.5 points
  • Cambridge English Language Assessment:
    Cambridge Certificate of Proficiency (CPE)
    Cambridge English: Certificate of Advanced English with grade A,B or C (CAE)
    Cambridge English: First Certificate with grade A (FCE)

When to take the test and how to upload the documentation:
The test result must not be more than two years old at the time of application.

The English language test should be taken before applying for admission and uploaded under “language skills documentation” in the online application form.

It is possible to apply for admission before you have taken the test. In this case documentation stating that you have signed up for a test (please state expected submission date) must be uploaded. If the test result is not part of the original application the test result is to be sent to sphd@psys.au.dk no later than one month after the application deadline.

The following applicants are exempted from documenting their English qualifications/taking a test:

  • Applicants with citizenship from the following countries: Australia, Canada, Ireland, New Zealand, the United Kingdom, the United States, or one of the Nordic countries (Denmark, Finland, Iceland, Norway or Sweden).
  • Applicants with a Bachelor’s or Master’s programme completed in Australia, Canada, Ireland, New Zealand, the United Kingdom, or the United States. In this case, please upload your Bachelor’s or Master’s diploma under the section ”Language skills documentation”.
  • Applicants with a Bachelor’s or Master’s programme completed at a Danish university for which the requirement was English B level at the time of admission. In this case, please upload your Bachelor’s or Master’s diploma under the section ”Language skills documentation”.

The programme committee may request further information or invite the applicant to attend an interview.

How to apply:
1) Find the application form:
Go to www.phd.scitech.au.dk/for-applicants/apply-here - Note, the online application system opens on 1 December 2019.
Choose February 2020 Call with deadline 1 February 2020 at noon (11.59 AM CET).
You will be directed to the call, and must choose the programme 'Nanoscience'.

2) Fill in the following information:

  • Personal information
  • Academic background
  • Admission
  • Financing (if any)
  • Study: In the dropdown menu you must choose the project: "Multifunctional biologics for enhanced tumor imaging, cell tracking and treatment"
  • Source (how you found out about the call)

Next to some of the information fields you will find a number. Click on the number to get further directions on how to fill in the information field/what information is needed.

3) Application attachments:
Please be aware that you cannot submit the application if one or several of these documents have not been uploaded.

If you wish to upload more than one document under each section, you must scan/merge all documents into one large PDF file and upload this. Please note that we reserve the right to remove scientific papers, large reports, theses and the like. Instead you can indicate a URL where the information is available.

All information in the application must be in English or Danish, preferably English.

As a minimum all applications must include (pdf-files only, max. 20 MB, no zip):

  • One reference (template for references)
  • Curriculum vitae,
  • Motivation (max. 1 page)
  • Transcripts, grade point averages (weighted and unweighted), and diploma(s) for both Bachelor’s and Master’s degree
  • Project description (½-4 pages). For technical reasons, you must upload a project description. When - as here - you apply for a specific project, please simply copy the project description above, and upload it as a PDF in the application. If you wish to, you can indicate an URL where further information can be found. Please note that we reserve the right to remove scientific papers, large reports, theses and the like.
  • Documentation of language skills if required.

After submission of the application, you will receive a confirmation e-mail with an application ID, you should use for reference if needed.

GSST reserves the right to verify the authenticity of your educational diploma and transcripts:

  • Request additional information to verify an application.
  • Reject the application if it is proven, or if the University has reasonable belief, that the information provided is false or if the applicant refuses to provide the requested information, whether or not an offer has already been made.
  • For further information on applying, assessment procedures, etc. please see the GSST Application Guide.

Please note:

  • The programme committee may request further information or invite the applicant to attend an interview.
  • The project will only be initiated if final funding (from GSST/the faculty) is secured.

All interested candidates are encouraged to apply, regardless of their personal background.


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Aarhus Universitet blev grundlagt i 1928 og er i dag i den absolutte verdenselite på flere forskningsfelter. Aarhus Universitet (AU) er blandt verdens 10 bedste universiteter grundlagt inden for de seneste 100 år og har en lang tradition for partnerskaber med nogle af verdens bedste forskningsinstitutioner og universitetsnetværk.

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