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PhD research in vivo assessment of glial functions at Center for Translational Neuromedicine

Københavns Universitet (KU)



Faculty of Health and Medical Sciences
University of Copenhagen

Two PhD research positions are available for assessment of glial functions in the brain of live rodents. The positions are for three years and starts 15 September 2020 or after agreement. The project will involve cell biology, molecular genetics, optical imaging, electrophysiology, and heuristic data analysis (i.e. requires Matlab, R, Python or similar programming skills). We welcome candidates with strong optic or electronic engineering background; or neuroscience background; Candidates are considered favourably if they have research experience in optical brain imaging, electrophysiology, general physiology, cell biology, and/or biochemistry. Candidates should have a Master’s degree in a relevant domain of physical, natural, or medical science with reasonable grades.

Center for Translational Neuromedicine currently has 50 employees and students and is divided into three labs. CTN is characterized by a highly ambitious research environment. The PhD Fellows will be co-supervised by Professor Nedergaard and Professor Hirase.

Being part of the Nedergaard/Hirase lab offers an opportunity to work in a multi-disciplinary lab engaged in neuroscience with a focus on the basic biology of glial cells in the CNS and the role of astrocytes in several neurological diseases, including stroke, spinal cord injury, epilepsy, tremor, and ALS. Research is aimed at defining neuroglia signaling under physiological conditions with the ultimate goal of defining new strategies for the treatment of neurological diseases that target astrocytic dysfunction. For examples of publications, please see Mestre et al. Science 2020; Dietz et al. Lancet Psychiatry 2020; Monai et al. PNAS, 2019.

CTN is part of the Faculty of Health and Medical Sciences, University of Copenhagen, and is located at Panum. The Center comprises modern laboratories and excellent facilities within neuroscience.

For more information: http://ctn.ku.dk/.

Your job
The main expectation of the PhD research is to investigate neuron-glia interactions together with the extracellular milieu in various stage of brain disease development. The target brain area of the project is the cerebral cortex and the input that influences locally or globally during cognitive processing. The individual PhD student’s project will be determined considering the candidate’s skills and experience.

Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

Essential experience and skills:

  • You have a Master’s degree in a relevant scientific area (e.g. neuroscience, physiology, biomedical engineering).
  • You have already been exposed to a related research environment (e.g., good programming experience for data analysis; in vivo optical imaging of the rodent brain (incl. surgery); molecular cloning and biochemical analysis skills.)
  • You have good knowledge in systems neuroscience.
  • Peer-reviewed publications in relevant or related fields are considered preferentially.
  • Proficient communication skills and ability to work in teams
  • Excellent English skills written and spoken

Formal requirements
The position is available for a three-year period.

The successful applicant will be requested to formally apply for enrolment as a PhD student at the Faculty of Health and Medical Sciences according to the rules stipulated in the Ministerial order on the PhD programme at the universities (PhD order) from the Ministry of Science, Innovation, and Higher Education and the guidelines for the PhD programme at the Faculty of Health and Medical Sciences.

Place of employment
The place of employment is at Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and state-of-the-art equipment.

Terms of employment
The employment as a PhD student is a full time and fixed-term position for 3 years. Starting date is in 15 September 2020 or after agreement.

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts at 27,590/ approx. 3,700 Euro (April 2020-level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of December 11, 2019.

You will report to Professor Hajime Hirase and Professor Maiken Nedergaard.

Questions
For further information, applicants may contact the supervisor Professor Nedergaard (nedergaard@sund.ku.dk) Professor Hajime Hirase (hirase@sund.ku.dk), or Administrator Ann Lee Christensen (ann.christensen@sund.ku.dk).

How to apply
Only online applications are accepted. The following must be included:

  • Cover letter stating the interest in and qualifications for the project, list of techniques, and three neuroscience papers published during 2018-2020 that the candidate has read. If the candidate is selected for an interview, the papers will be discussed.
  • Full CV
  • Diploma and transcripts of records, both from Bachelor’s and Master’s degrees
  • Publication list (optional)
  • Possible reference contacts (name and e-mail)

Application deadline is 8 June 2020, 23.59 CET.
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the above-mentioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.

Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held in week 27.

The Faculty of Health and Medical Sciences comprises approximately 7850 students, 1700 PhD students and 4800 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community. The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.

Københavns Universitet giver sine knap 10.000 medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.

Kontakt
Ann Lee Berger Christensen
E-mail: ann.christensen@sund.ku.dk

Kontakt
Maiken Nedergaard
E-mail: nedergaard@sund.ku.dk

Kontakt
Hajime Hirase
E-mail: hirase@sund.ku.dk

Info
Ansøgningsfrist: 08-06-2020

Ansættelsesdato: 15-09-2020

Arbejdstid: Fuldtid

Afdeling/Sted: Center for Translational Neuromedicine

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Københavns Universitet (KU)
Københavns Universitet (KU)
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