DTU Studieprojekt - How linear are the MR Transmission (Tx) coils B1 correction for quantitative variable flip angle T1 maps in myocardium.

How linear are the MR Transmission (Tx) coils B1 correction for quantitative variable flip angle T1 maps in myocardium.

Udbyder
Vejleder
Sted
København og omegn
Magnetic Resonance Imaging (MRI) is a non-ionizing form of medical imaging which enables tomographic imaging of the human body for diagnosing, characterizing, and studying diseases in vivo. The current clinical MR scanners, however, generate qualitative data with no easy way to be compared across population, MR sites and over time.

Developing quantitative measures in MR show promise not only for benefits such as allowing comparisons over population, sites and time but also may allow earlier diagnosis and treatment of the disease or treatment which may halt or even reverse the damage from the disease.

T1- relaxation time maps showed a promising way to quantitatively characterise the tissues of organs non-invasively in vivo. The quantitative T1 measures are sensitive for the radiofrequency (RF) field (called B1). Therefore, this project focuses on analysing and validating Coils and B1 field mapping methods for quantitative T1 measures. The project can be divided into subprojects:

1- Determining the linearity of the preclinical and clinical coils (1 student).

2- Comparison and validation of some magnitude-base/phase sensitive B1 correction methods at a range of low flip angles for cardiac imaging (1-2 students).

3- Estimation the impact of B1- correction method on variable flip angle T1 maps of the myocardial tissues.(1 student)

The experiments will run on clinical 1.5/3T scanners and a preclinical 9.4 T MR small animal scanner at Panum. The candidate students will work in a highly interdisciplinary environment having the opportunity to collaborate with people from imaging centers, the university and clinics.

Allowed no of students per report: 3-4

I samarbejde med
Biomedical Institute, Copenhagen university

Forudsætninger
Basic MATLAB programming, basic MR physics and basic image science.

Emneord

• Bioteknologi og biokemi
• Medicin og medicoteknik
• Billedanalyse
• Fysiologisk modellering
• Høreapparater
• Hospitalsindretning
• Kunstige organer
• Medicinske apparater og systemer
• Nanomedicin
• Radioaktive lægemidler og isotoper
• Sundhed og sygdomme

• BiomedicalEngineering
• DTUhealthtech

Navn
Nina Kjærgaard Hendel

Stilling
Specialkonsulent

Mail
ninak@dtu.dk

Vejleder-info
Bachelor i Medicin og Teknologi
Vejleder
Nina Kjærgaard Hendel

Type
Bachelorprojekt, Kandidatspeciale

Bachelor i Kvantitativ Biologi og Sygdomsmodellering
Vejleder
Nina Kjærgaard Hendel

Type
Bachelorprojekt, Kandidatspeciale

Kandidatuddannelsen i Kvantitativ Biologi og Sygdomsmodellering
Vejleder
Nina Kjærgaard Hendel

Type
Bachelorprojekt, Kandidatspeciale

Kandidatuddannelsen i Medicin og Teknologi
Vejleder
Nina Kjærgaard Hendel

Type
Bachelorprojekt, Kandidatspeciale