Postdoc in NMR based structural studies of RNA riboswitches - DTU Chemistry

We welcome applicants for a three-year postdoc position at the Department of Chemistry, DTU and the NMR Center • DTU. In this position, you will engage in exciting research related to structural and dynamics studies of RNA riboswitches using mainly NMR spectroscopy as well as their in vitro expression.
We welcome applicants for a three-year postdoc position at the Department of Chemistry, DTU and the NMR Center • DTU. In this position, you will engage in exciting research related to structural and dynamics studies of RNA riboswitches using mainly NMR spectroscopy as well as their in vitro expression. The position will be in the NMR spectroscopy research group headed by Assoc. Prof. Charlotte H. Gotfredsen.

The position offers an opportunity to work with a dynamic and multi-disciplinary project. You will carry out research in a team engaged in multiple NMR projects in the field of RNA structural studies, fragment-based drug discovery screening and studies of interactions with their targets (RNA or protein), natural product, the identification of new structural scaffolds and in-situ NMR based metabolomics. The research project will provide opportunities to synthesize RNA using both in vitro transcription and chemically, preform NMR based structural elucidation of the fluorine responsive riboswitch apo and holo form as well as study the dynamic and kinetic structural impact of different ligands and ions on RNA structures. In this position you will also have opportunities to work with undergraduate and graduate students.

The University
DTU is located in the greater Copenhagen area, which is acknowledged for its excellent standards of living, childcare, and welfare system.

An interest in structural biology and a desire to work in an interdisciplinary environment
We are looking for a profile witha documented track record in NMR spectroscopy of biomolecules and knowledge within the field of RNA studies. You show a strong commitment to research, and you are enthusiastic about working with research students. You like to drive research and take ownership of your project and direction but also thrive in a team working closely together and feeding off each other’s ideas.

As a formal qualification, you must hold a PhD degree (or equivalent) in structural biology or chemical biology and a strong theoretical and experimental background in NMR spectroscopy and knowledge within structural biology.

Open-minded knowledge sharing and constructive teamwork are keys to the success of the overall project. Additionally, your CV comprises:

• A thorough interest in NMR spectroscopy applied to structural biology.
• Experience with production of RNA using synthesis and/or in vitro transcription.
• Experience with the use of computational tools in structural biology.
• A track record of communicating research results.

In the assessment of the candidates, consideration will be given to:

• Relevance of education and previous experience.
• Passion for research and scientific discoveries.
• Proficiency in written and spoken English and good communication skills.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

The period of employment is 36 months. Starting date is June 1, 2024 (or according to mutual agreement). The position is a full-time position.

You can read more about career paths at DTU here.
Further information
Further information may be obtained from Associate Professor Charlotte H. Gotfredsen, Department of Chemistry, [email protected]

You can read more about DTU Chemistry at www.kemi.dtu.dk and more about the research group at www.nmrcenter.kemi.dtu.dk/english.

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

Application procedure
Your complete online application must be submitted no later than 17 May 2024 (23:59 Danish time).
We will be evaluating the candidates as they come in also prior to the application deadline.
Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

• Application (cover letter)
• CV, including a list of publications and contact information for at least two references
• Academic Diplomas (MSc/PhD – in English)

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

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