Postdoc in ion channel research at Department of drug design and pharmacology

We are looking for a highly motivated and dynamic postdoc for a 10 month position with a start date of 1.3.2026.

Mechanistic basis for modulation of the sodium leak (NALCN) channelosome by G proteins.

Information on the department can be found at: www.ilf.ku.dk

Our research
We are an international team working on interdisciplinary approaches to study ion channel function and pharmacology with a focus on protein-protein interactions.We provide a competitive and inclusive environment.

Your job
In this project we strive to understand how the sodium leak (NALCN) channelosome is modulated by G proteins. Your tasks would be to employ a combination of electrophysiological, biochemical, molecular biology / protein engineering approaches to delineate the mechanism of action by which G proteins modulate NALCN currents in heterologous expression systems.
Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

Essential experience and skills:

• You have a PhD in pharmacy or biochemistry
• You are highly experienced in electrophysiology, molecular biology, protein engineering, biochemistry
• You have an active interest in laboratory organisation and making laboratory science more environmentally friendly
• Proficient communication skills and ability to work in teams
• Excellent English skills written and spoken

Desirable experience and skills:

• Practical experience two-electrode voltage clamp and patch clamp electrophysiology, ion channel-related pharmacology, cloning, split intein-mediated protein splicing and Western blots
• Practical experience in implementing electronic lab books and laboratory efficiency schemes such as the LEAF program
• Co-authorship in leading peer-reviewed journals with at least one as (co-)first author
• Invitations to speak at international meetings

Place of employment
The place of employment is at the Department of drug design and pharmacology, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and facilities for electrophysiological and and pharmacological investigation of ion channels.

Terms of employment
The average weekly working hours are [timer] hours per week.

The position is a fixed-term position limited to a period of 10 months. The starting date is 1.3.2026.

Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 35,000 DKK/approx. 4,700 EUR (October 2021 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the Job Structure for Academic Staff at Universities 2020.

Questions
For further information please contact Prof Stephan Pless ([email protected]); www.sund.ku.dk
Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

• Motivated letter of application (max. one page).
• CV incl. education, work/research experience, language skills and other skills relevant for the position.
• A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
• List of publications.

Deadline for applications: 14 Decemberr 2025, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held in week 2.

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.

Københavns Universitet giver sine knap 10.000 medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.

Kontakt
Stephan Pless
E-mail: [email protected]

Info
Ansøgningsfrist: 14-12-2025

Ansættelsesdato: 01-03-2026

Arbejdstid: Fuldtid

Afdeling/Sted: Department of Drug Design and Pharmacology