Postdoc in Cancer Epigenetics at Center for Protein Research

We are looking for a highly motivated and dynamic postdoc with expertise in chromatin biology to develop new epigenetic approaches for cancer treatment. This is a 3-year position with start 15 November 2024, or after agreement.

The successful candidate will work at the Novo Nordisk Foundation Center for Protein Research (CPR) in the Chromatin Replication and Epigenome Maintenance research group headed by Prof. Anja Groth.

More information on the CPR can be found at: https://www.cpr.ku.dk

Our research
The focus of the Groth group is to elucidate how chromatin organization and function is propagated during mitotic cell division to maintain genome and epigenome stability. Our goal is to understand mechanisms that underpin chromatin replication and epigenetic cell memory, and how they impact on cell fate decisions in development and disease. We apply innovative proteomic and genomic approaches in combination with stem cell biology, high-content imaging, chromatin biochemistry and structure-function studies. Our group is diverse and multidisciplinary with many scientific collaborations nationally and internationally, and we have an inclusive and highly collaborative work culture. We value idea sharing and use Creative Problem Solving tools to develop our research projects. We also have a translational focus connected to our spin-out company Ankrin Therapeutics.

The Groth Group is part of the Protein Memory Program at NNF CPR, a multidisciplinary and international research center with a highly collaborative research environment and cutting-edge core facilities, such as genomics, proteomics, protein imaging, protein production and characterization, big data management platforms. In 2025 the Groth group plans to move to the Danish Cancer Institute (DCI), a part of Danish Cancer Society, and a leading international cancer research institute with topnotch laboratory and computational facilities.

Your job
You will be part of our efforts to translate our research in epigenetics into innovative treatment strategies together with our clinical collaborators. Building on our expertise in chromatin replication, the project will develop rationale for novel epigenetic approaches for cancer treatment. You will use genome-editing approaches along with state-of-the-art genomics to address how modulation of chromatin assembly impacts epigenetic landscapes and genome function in relevant cancer models. You will be part of a highly collaborative group and we expect that you will contribute to our other ongoing projects and supervision of students.

Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

• A PhD in Life science, biochemistry, molecular cell biology, cancer biology or related
• Background in epigenetics and cancer biology.
• Expertise in next-generation sequencing (NGS) approaches and data analysis.
• Collaborative and inclusive mindset and curiosity driven nature
• Good communication and organization skills
• Excellent English skills written and spoken
  

Place of employment
The employment is at CPR (www.cpr.ku.dk), a Novo Nordisk Foundation center of excellence established in 2007 and embedded in the Faculty of Health and Medical Sciences, University of Copenhagen, to promote basic and applied research on human proteins of medical relevance. The Center comprises modern laboratories, supercomputer resources and state-of-the- art facilities within protein science and genomics. CPR is an interdisciplinary international environment with English as the main language. We are located in central Copenhagen, a city with one of the highest qualities of life in the world and a vibrant and highly interactive research environment. The University of Copenhagen has a strong focus on balancing professional life with a family-friendly working environment https://www.ism.ku.dk/faq.

Terms of employment
The employment as postdoc is a full time and fixed-term position for 3 years. Starting date is 15 November 2024 or after agreement.

Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 35,000 DKK/approx. 4,700 EUR (October 2021 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the Job Structure for Academic Staff at Universities 2020.

Questions
For further information please contact Prof. Anja Groth; e-mail anja.groth @cpr.ku.dk
Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

• Motivated letter of application (max. one page).
• CV incl. education, work/research experience, language skills and other skills relevant for the position and names and contact details for 3 references.
• A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
• List of publications.

Deadline for applications: 15 September 2024, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held in week 40-41

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.

Københavns Universitet giver sine knap 10.000 medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.

Kontakt
Anja Groth
E-mail: [email protected]

Info
Ansøgningsfrist: 15-09-2024

Ansættelsesdato: 15-11-2024

Arbejdstid: Fuldtid

Afdeling/Sted: Novo Nordisk Foundation Center for Protein Research